产品说明
一般描述
Saccharin is a well-known non-carbohydrate, sulfonyl amide artificial sweetener and is generally used in the form of its calcium or sodium salt. It possesses a sweetening power of about 550 times more than that of saccharose. On losing the acidic imino hydrogen, it forms the corresponding nitro anion, which exhibits interesting coordination chemistry. It offers a bitter and metallic aftertaste which limits its use as an artificial sweetening agent.
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards.
应用
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Saccharin can be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatographic and spectrophotometric techniques.
生化/生理作用
哺乳动物的甜促味剂。有人提出,果蝇具有葡萄糖特异性甘油味觉受体结合位点。
分析说明
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
其他说明
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
附注
To see an example of a Certificate of Analysis for this material enter LRAC3561 in the slot below. This is an example certificate only and may not be the lot that you receive.
基本信息
经验(实验)分子式 | C7H5NO3S |
分子量 | 183.18 |
Beilstein | 6888 |
EC 号 | 201-321-0 |
MDL编号 | MFCD00005866 |
PubChem化学物质编号 | 329823326 |
NACRES | NA.24 |
产品性质
质量水平 | 300 |
等级 | certified reference material pharmaceutical secondary standard |
CofA | current certificate can be downloaded |
technique(s) | HPLC: suitable gas chromatography (GC): suitable |
mp | 226-229 ℃ (lit.) |
application(s) | pharmaceutical (small molecule) |
格式 | neat |
药典可追溯性 | traceable to PhEur S0040000 traceable to USP 1607007 |
储存温度 | 2-30℃ |
SMILES string | O=C1NS(=O)(=O)c2ccccc12 |
InChI | 1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9) |
InChI key | CVHZOJJKTDOEJC-UHFFFAOYSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
SUPELCO