2-(N-[m-羟基苯基]-p-甲苯氨基甲基)咪唑啉

产品名称：

65-28-1
Phentolamine Mesylate
2-(N-[m-Hydroxyphenyl]-p-toluidinomethyl)imidazoline
Phentolamine methanesulfonate salt
酚妥拉明
酚妥拉明甲磺酸盐
2-(N-[m-羟基苯基]-p-甲苯氨基甲基)咪唑啉

产品介绍：

产品说明

一般描述

Phentolamine Mesylate belongs to the class of alpha adrenergic antagonist drugs. It is used in the treatment of pheochromocytoma-related hypertension, erectile dysfunction and in the diagnosis of pheochromocytoma and norepinephrine-related dermal necrosis.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Phentolamine Mesylate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chemiluminescence technique.

生化/生理作用

α-肾上腺素受体拮抗剂；外周血管舒张剂。

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC3261 in the slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

线性分子式	C₁₇H₁₉N₃O · CH₃SO₃H
分子量	377.46
EC 号	200-604-6
MDL编号	MFCD00134201
PubChem化学物质编号	329823376
NACRES	NA.24

产品性质

质量水平	300
等级	certified reference material pharmaceutical secondary standard
CofA	current certificate can be downloaded
technique(s)	HPLC: suitable gas chromatography (GC): suitable
mp	180-182 ℃ (lit.)
application(s)	pharmaceutical (small molecule)
格式	neat
药典可追溯性	traceable to PhEur Y0001127 traceable to USP 1530004
储存温度	2-30℃
SMILES string	CS(O)(=O)=O.Cc1ccc(cc1)N(CC2=NCCN2)c3cccc(O)c3
InChI	1S/C17H19N3O.CH4O3S/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15;1-5(2,3)4/h2-8,11,21H,9-10,12H2,1H3,(H,18,19);1H3,(H,2,3,4)
InChI key	OGIYDFVHFQEFKQ-UHFFFAOYSA-N
Gene Information	human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152)

安全信息

象形图
警示用语：	Warning
危险声明	H302 - H315 - H319 - H335
预防措施声明	P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类	Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable