利托那韦

产品名称：

155213-67-5
Ritonavir
1,3-Thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[[(2S)-3-methyl-2-[[methyl-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]carbamoyl]amino]butanoyl]amino]-1,6-diphenylhexan-2-yl]carbamate
10-Hydroxy-2-methyl-5-(1-methylethyl)-1-[2-(1-methylethyl)-4-thiazolyl]-3,6-dioxo-8,11-bis(phenylmethyl)-2,4,7,12-tetraazatridecan-13-oic acid, 5-thiazolylmethyl ester, [5S-(5R*, 8R*, 10R*, 11R*)]
利托那韦

产品介绍：

产品说明

一般描述

Ritonavir belongs to the group of protease inhibitors, which block the part of HIV called protease. Its mode of action involves binding to the protease active site and inhibiting the activity of the enzyme.
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Ritonavir may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using chromatography techniques.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAB9120 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式	C₃₇H₄₈N₆O₅S₂
分子量	720.94

产品性质

质量水平	300
生物来源	synthetic
等级	certified reference material pharmaceutical secondary standard
agency	BP EP USP
蒸汽压	<0.0000001 kPa ( 25 ℃)
形式	powder
CofA	current certificate can be downloaded
包装	pkg of 1 g
储存条件	protect from light
technique(s)	HPLC: suitable gas chromatography (GC): suitable
颜色	white to tan
溶解性	acetonitrile: slightly soluble ethanol: freely soluble methanol: freely soluble methylene chloride: freely soluble water: practically insoluble
application(s)	pharmaceutical (small molecule)
格式	neat
药典可追溯性	traceable to PhEur Y0000714 traceable to USP 1604803
运输	ambient
储存温度	2-30℃
InChI	1S/C37H48N6O5S2/c1-24(2)33(42-36(46)43(5)20-29-22-49-35(40-29)25(3)4)34(45)39-28(16-26-12-8-6-9-13-26)18-32(44)31(17-27-14-10-7-11-15-27)41-37(47)48-21-30-19-38-23-50-30/h6-15,19,22-25,28,31-33,44H,16-18,20-21H2,1-5H3,(H,39,45)(H,41,47)(H,42,46)/t28-,31-,32-,33-/m0/s1
InChI key	NCDNCNXCDXHOMX-XGKFQTDJSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302 + H312 + H332
预防措施声明	P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312
危险分类	Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable