4-羟基吡唑并 (3,4-d) 嘧啶

产品名称：

315-30-0
Allopurinol
4-Hydroxypyrazolo(3,4-d)pyrimidine
HPP
1H-Pyrazolo(3,4-d)pyrimidin-4-ol
4-Hydroxypyrazolo[3,4-d]pyrimidine
别嘌醇
1H-吡唑并 (3,4-d) 嘧啶-4-醇
4-羟基吡唑并 (3,4-d) 嘧啶
4-羟基吡唑并 [3,4-d] 嘧啶

产品介绍：

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Allopurinol is a drug used in the treatment of chronic gout or hyperuricaemia. Its mode of action involves inhibition of xanthine oxidase, an important enzyme catalyzing the hydroxylation of hypoxanthine to xanthine and xanthine to uric acid.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Allopurinol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by spectrophotometry.

生化/生理作用

黄嘌呤氧化酶和初始嘧啶生物合成的抑制剂。治疗高尿酸血症和痛风的经典药物。

分析说明

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA1633 in the slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式	C₅H₄N₄O
分子量	136.11
EC 号	206-250-9
MDL编号	MFCD00599413
PubChem化学物质编号	329823354
NACRES	NA.24

产品性质

质量水平	300
等级	certified reference material pharmaceutical secondary standard
CofA	current certificate can be downloaded
technique(s)	HPLC: suitable gas chromatography (GC): suitable
mp	>300 ℃ (lit.)
application(s)	pharmaceutical (small molecule)
格式	neat
药典可追溯性	traceable to BP 870 traceable to PhEur A0350000 traceable to USP 1013002
储存温度	2-30℃
SMILES string	O=C1NC=Nc2[nH]ncc12
InChI	1S/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10)
InChI key	OFCNXPDARWKPPY-UHFFFAOYSA-N
Gene Information	human ... XDH(7498)

安全信息

象形图
警示用语：	Danger
危险声明	H301 - H317
预防措施声明	P280 - P301 + P310 + P330 - P302 + P352
危险分类	Acute Tox. 3 Oral - Skin Sens. 1
储存分类代码	6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable