法莫替丁

产品名称：

76824-35-6
Famotidine
{3-[((2-((Aminoiminomethyl)amino)-4-thiazolyl)methyl)thio]-N′-(aminosulfonyl)propaneimidamide}
N′-(Aminosulfonyl)-3-([2-(diaminomethyleneamino)-4-thiazolyl]methylthio)propanamidine
法莫替丁

产品介绍：

产品说明

一般描述

Famotidine is a histamine H2-receptor antagonist, which promotes the healing of erosive esophagitis, gastric and duodenal ulcers since it inhibits the gastric acid secretion in humans.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Famotidine may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using different chromatography techniques.

生化/生理作用

H₂ histamine receptor antagonist; anti-ulcer agent

分析说明

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA7133 in the slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式	C₈H₁₅N₇O₂S₃
分子量	337.45
MDL编号	MFCD00079297
PubChem化学物质编号	329823085
NACRES	NA.24

产品性质

质量水平	300
生物来源	synthetic
等级	certified reference material pharmaceutical secondary standard
agency	BP EP USP
蒸汽压	<0.0000001 kPa ( 25 ℃)
CofA	current certificate can be downloaded
包装	pkg of 1 g
储存条件	protect from light (20 mm aluminium crimp seal for unused portion)
technique(s)	HPLC: suitable gas chromatography (GC): suitable
颜色	white to pale yellow-white
mp	325.4-327.2 °F (163—164℃)
溶解性	DMF: freely soluble acetone: practically insoluble chloroform: practically insoluble ethanol: practically insoluble ether: practically insoluble ethyl acetate: practically insoluble glacial acetic acid: freely soluble methanol: slightly soluble water: very slightly soluble
application(s)	pharmaceutical (small molecule)
格式	neat
药典可追溯性	traceable to BP 653 traceable to PhEur F0050000 traceable to USP 1269200
运输	ambient
储存温度	2-8℃
SMILES string	N\C(N)=N\c1nc(CSCCC(=N)NS(N)(=O)=O)cs1
InChI	1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14)
InChI key	XUFQPHANEAPEMJ-UHFFFAOYSA-N
Gene Information	human ... HRH2(3274)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable