产品说明
一般描述
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Flucytosine is an antimycotic drug that can be effectively utilized against severe Candida and Cryptococcus infections.
应用
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Flucytosine may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques.
生化/生理作用
具有抗真菌活性的核苷类似物。5-氟胞嘧啶通过胞嘧啶脱氨酶脱氨，得到 5-氟尿嘧啶，从而导致 RNA 错编。5-氟胞嘧啶抑制 DNA 和 RNA 的合成并干扰核糖体蛋白的合成。
分析说明
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
其他说明
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
附注
To see an example of a Certificate of Analysis for this material enter LRAA5760 in the slot below. This is an example certificate only and may not be the lot that you receive.
基本信息
| 经验(实验)分子式 | C4H4FN3O |
| 分子量 | 129.09 |
| Beilstein | 127285 |
| EC 号 | 217-968-7 |
| MDL编号 | MFCD00006035 |
| PubChem化学物质编号 | 329823537 |
产品性质
| 质量水平 | 300 |
| 等级 | certified reference material pharmaceutical secondary standard |
| CofA | current certificate can be downloaded |
| 包装 | pkg of 1 g |
| technique(s) | HPLC: suitable gas chromatography (GC): suitable |
| mp | 298-300 ℃ (dec.) (lit.) |
| application(s) | pharmaceutical (small molecule) |
| 格式 | neat |
| 药典可追溯性 | traceable to PhEur F0175000 traceable to USP 1272000 |
| 储存温度 | 2-30℃ |
| SMILES string | NC1=NC(=O)NC=C1F |
| InChI | 1S/C4H4FN3O/c5-2-1-7-4(9)8-3(2)6/h1H,(H3,6,7,8,9) |
| InChI key | XRECTZIEBJDKEO-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H361 |
| 预防措施声明 | P281 |
| 危险分类 | Repr. 2 |
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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