产品说明
一般描述
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
生化/生理作用
8-甲氧基补骨脂素 (8-MOP) 加 A 波紫外线 (UVA) 辐射可诱导单加合物形成和 DNA 链间交联,因此可用于研究 DNA 修复和重组机制。培养的正常人黑素细胞经 8-甲氧基补骨脂素处理和 A 波紫外线 (UVA) 照射后形成 8-甲氧基补骨脂素-磷脂光加成产物,经二酰甘油取代后可在无细胞体系中激活蛋白激酶 C。8-MOP 是纯化重组细胞色素 P450 的灭活剂。它还可以通过抑制 [Ca2+] 的升高,而抑制从 P 物质激活的大鼠腹膜肥大细胞的 P 物质诱导型组胺释放。
分析说明
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
其他说明
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
基本信息
经验(实验)分子式 | C12H8O4 |
分子量 | 216.19 |
Beilstein | 196453 |
MDL编号 | MFCD00005009 |
产品性质
等级 | certified reference material pharmaceutical secondary standard |
CofA | current certificate can be downloaded |
包装 | pkg of 500 mg |
mp | 148-150 ℃ (lit.) |
application(s) | pharmaceutical |
药典可追溯性 | traceable to USP 1417001 |
储存温度 | 2-30℃ |
SMILES string | COc1c2OC(=O)C=Cc2cc3ccoc13 |
InChI | 1S/C12H8O4/c1-14-12-10-8(4-5-15-10)6-7-2-3-9(13)16-11(7)12/h2-6H,1H3 |
InChI key | QXKHYNVANLEOEG-UHFFFAOYSA-N |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H302 - H317 |
预防措施声明 | P261 - P264 - P270 - P280 - P301 + P312 - P302 + P352 |
危险分类 | Acute Tox. 4 Oral - Skin Sens. 1 |
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
SUPELCO