3-Carboxy-4-methyl-5-propyl-2-furanpropanoic acid

产品名称：

86879-39-2
3-Carboxy-4-methyl-5-propyl-2-furanpropanoic acid
CMPF
Propylurofuranic acid
3-Carboxy-4-methyl-5-propyl-2-furanpropionic acid

产品介绍：

产品说明

一般描述

3-Carboxy-4-methyl-5-propyl-2-furanpropanoic acid (CMPF), a major metabolite of furan fatty acids, is a uremic toxin (UT), excreted into the urine via organic,anion transporters under physiological conditions. It is mostly reported to be accumulated in chronic kidney disease (CKD) patients. Monitoring of CMPF may be important to predict organic anion transporting polypeptide (OATP)1B activity in CKD patients as studies have implicated a decreased trend in (OATP)1B activity in patients with this uremic toxin. It is also found to be in increased concentrations, for patients who progress from prediabetes to type 2 diabetes, patients with renal failure, polyunsaturated fatty acids with high-temperature cooking and subjects who consume fish or fish oil.

应用

3-Carboxy-4-methyl-5-propyl-2-furanpropanoic acid may be used as an analytical reference standard for the quantification of the analyte in human plasma samples using ultra-high performance liquid chromatography coupled to tandem mass spectrometry (UHPLC–MS/MS).

基本信息

经验(实验)分子式	C₁₂H₁₆O₅
分子量	240.25
MDL编号	MFCD08436079
NACRES	NB.21

产品性质

等级	analytical standard
质量水平	100
测定	≥95.0% (HPLC)
保质期	limited shelf life, expiry date on the label
application(s)	clinical testing
格式	neat
储存温度	2-8℃
SMILES string	OC(CCC1=C(C(O)=O)C(C)=C(CCC)O1)=O
InChI	1S/C12H16O5/c1-3-4-8-7(2)11(12(15)16)9(17-8)5-6-10(13)14/h3-6H2,1-2H3,(H,13,14)(H,15,16)
InChI key	WMCQWXZMVIETAO-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3