4-二甲胺基苯基偶氮苯磺酰氯

产品名称：

56512-49-3
4-(Dimethylamino)azobenzene-4′-sulfonyl chloride
4-(4-Dimethylaminophenylazo)benzenesulfonyl chloride
DABS-Cl
Dabsyl chloride
4-(二甲氨基)偶氮苯-4′-磺酰氯
4-二甲胺基苯基偶氮苯磺酰氯
4-(N,N-二甲基氨基)偶氮苯-4'-磺酸氯

产品介绍：

产品说明

一般描述

Amino groups are common to many biological compounds and many amines used in pharmaceuticals. Most of these compounds show weak absorption in direct HPLC analysis with UV-VIS detection. However, strongly absorbing derivatives of amines can be easily detected by HPLC with high sensitivity even when present at low concentrations. Primary and secondary amino groups are usually derivatized as aromatic derivatives by nucleophilic substitution reactions using reagents such as arylsulfonyl chlorides.
4-(Dimethylamino)azobenzene-4′-sulfonyl chloride, a well-known UV-labeling agent, is generally used for the derivatization of N-terminal amino acids, imidazole derivatives, polyamines, etc. prior to their chromatographic determination due to the former′s capacity to covalently bind to the substrates. Its derivatives typically absorb UV radiation between the range of 436-460 nm. This method of derivatization is regarded as superior compared to other methods owing to the simplicity of the procedure, high stability and reproducibility, best resolution of the analytes, etc.

应用

4-(Dimethylamino)azobenzene-4′-sulfonyl chloride may be used to derivatize biogenic amines, primary amino acids, melamine, and hydroxyproline and proline extracted from various biological samples prior to their determination using high performance liquid chromatography (HPLC) technique to increase their detection sensitivity.

推荐产品

Discover LiChropur^™ reagents ideal for HPLC or LC-MS analysis

法律信息

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

基本信息

线性分子式	(CH₃)₂NC₆H₄N=NC₆H₄SO₂Cl
分子量	323.80
Beilstein	3064095
EC 号	260-235-1
MDL编号	MFCD00007444

产品性质

质量水平	100
等级	for HPLC derivatization
测定	98.0-102.0% (AT)
质量	LiChropur^™
technique(s)	HPLC: suitable
mp	185 ℃ (dec.) (lit.)
SMILES string	CN(C)c1ccc(cc1)\N=N\c2ccc(cc2)S(Cl)(=O)=O
InChI	1S/C14H14ClN3O2S/c1-18(2)13-7-3-11(4-8-13)16-17-12-5-9-14(10-6-12)21(15,19)20/h3-10H,1-2H3/b17-16+
InChI key	VTVWTPGLLAELLI-WUKNDPDISA-N

安全信息

象形图
警示用语：	Danger
危险声明	H314
预防措施声明	P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
危险分类	Skin Corr. 1B
储存分类代码	8B - Non-combustible, corrosive hazardous materials
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable